Maternal fish oil supplement decreases the incidence of IgE-associated disease in infants for the first 2 years of life

This trial involved 145 pregnant women on a dose of either 1.6g EPA and 1.1g DHA or a placebo. The intake of EPA/DHA or placebo began in the 25th gestational week and continued through 3.5 months of breastfeeding. No significant difference in prevalence of allergy between the groups was found. However, the incidence of IgE-associated disease was lower in the group that had fish oil supplementation compared to the placebo group (13% vs. 30%, p=0.01). Furthermore, maternal and infant levels of DHA and EPA were associated with this lower prevalence of IgE-associated disease in a dose-dependent manner. Although omega-3 supplement may not have obvious preventative effect on the prevalence of allergy, it did decrease the cumulative incidence of IgE-associated disease during the first 2 years of life. Higher levels of DHA and EPA in the plasma were associated with less IgE-associated disease and a reduced severity of allergy.

Fish oil-Natural(Tuna) which contains DHA and EPA are present in PM Procare (Pregnancy & Breastfeeding formulation) and PM Bright Kids (for children’s eye, neural and immune health).

Furuhjelm, C., et al., Allergic disease in infants up to 2 yr of age in relation to plasma omega-3 fatty acids and maternal fish oil supplementation in pregnancy and lactation. Pediatr Allergy Immunol, 2011.